Description
SS-31 (elamipretide) is a synthetic mitochondria-targeted compound studied for its interaction with cardiolipin on the inner mitochondrial membrane. In preclinical research, it has been investigated for its proposed role in supporting electron transport chain efficiency and ATP synthesis in cellular and animal models of mitochondrial stress.
Laboratory studies have explored SS-31 side effects on reactive oxygen species (ROS) production and membrane lipid peroxidation in mitochondrial dysfunction models. It has been studied in the context of research into rare mitochondrial disorders, including Barth syndrome and primary mitochondrial myopathy, as well as in animal models of aging-related muscle and cardiac tissue changes, and in kidney and neurological injury models
Studies include the following subjects:
- Enhanced Cellular Energy: Binds to cardiolipin to stabilize the electron transport chain, optimizing ATP (energy) production.
- Reduced Oxidative Stress: Acts as a powerful antioxidant that scavenges reactive oxygen species (ROS) inside mitochondria.
- Heart and Muscle Support: Studied for improving cardiac function in heart failure models and increasing fatigue resistance or endurance in aging muscle tissue.
- Organ Protection: Shown in research to mitigate ischemia-reperfusion injury, acute kidney injury, and age-related cognitive decline
Elamipretide has been investigated in human clinical trials for mitochondrial disease indications; it is not an FDA-approved drug product.
This listing does not offer that investigational product — it is sold strictly as a research reagent, distinct from any clinical trial material, and is not intended for human use.
SS-31 is supplied as 10mg lyophilized powder, ≥99% purity, third-party verified. For laboratory research applications only. Not for human consumption, diagnostic, or therapeutic use. Certificate of Analysis available on request. Store at -20°C.
CAS Number: 736992-21-5
SEQUENCE: D-Arg-Dmt-Lys-Phe-NH2
Amino Acid Chain Length: 4
Molecular Formula: C32H49N9O5
• For Research use only
• Not for human use
• 99% Pure
• Independent Lab Tested

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